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The disadvantages are slightly lower efficacy and the requirement for daily use rather than weekly injections. GLP-1 medications work by suppressing appetite

1 As it relates to CKD progression, if the study proves effective with respect to GFR, it will be interesting to note the efficacy relative to other drugs with similar proven effects such as SGLT2 inhibitors

Ozempic is primarily used for managing type 2 diabetes, while Wegovy is specifically approved for weight loss in individuals with obesity or overweight conditions

Skinny Shot Cost Breakdown Sources: Healthline, American Medical Association 2024, Gallup/Statista (12.4% GLP-1 usage 2025), Grand View Research ($13.84B GLP-1 market 2024), J.P

Front Aging Neurosci 9:265474